Sun G, Casey S, Hill E, Farrokhi F, Vaezi M. Am Coll of Gastroenterology. 2007;102(2).
OBJECTIVES: Our aim was to provide data for Dx-pH probes in the oropharyngeal and distal esophageal sites in normal subjects.
RESULTS: A total of 31 normal subjects (11 M/ 20 F); mean age 33.2 yrs (range 21–56) comprised the study population. The median (95th percentile) total% time below pH4, 5, and 6 in the distal esophagus was 1.0 (5.3), 2.9 (12.6), and 10.4 (46.1), respectively (Table 1). For the oropharyngeal proximal probe, the median (95th percentile)% time below pH 4, 5, and 6 was 0.0 (0.0), 0.0 (2.4), and 1.0 (22.5), respectively. Finally, for the proximal probe, the median (95th percentile) number of events below pH 4, 5, and 6 was 0.0 (0.6), 0.0 (8.4), and 4.1 (197.5), respectively, over a 24 hour period in this normal population.
CONCLUSION: The normative values for the new Dx-pH catheter probe compares favorably to the accepted gold standard pH monitoring device. Future studies can focus on comparative evaluations between patients with and without GERD using the Dx-pH catheter probe.