“First Direct Correlation of Proton Pump (H/K-atpase) Expression in Human Laryngeal Epithelium with Pharyngeal pH Monitoring in Patients with Suspected Laryngopharyngeal Reflux”September 8, 2017
“Pharyngeal pH Monitoring Better Predicts a Successful Outcome for Extraesophageal Reflux Symptoms After Antireflux Surgery”September 8, 2017
Mazzoleni G, Vailati C, Lisma DG, Testoni PA, Passaretti S. Neurogastroenterol Motil. 2014 Nov;26(11):1557-64.
OBJECTIVES: Aim of this study is to examine the correlation between OP pHmetry and esophageal pHMII monitoring.
RESULTS: 2394 refluxes were detected by pHMII; of these only 120 were detected also by OP Dx-probe. On the other hand, the proportion of OP pH events which were temporally related to an episode of distal reflux ranged from 0% to 17%, depending on the proximal pH criteria used. In 8/36 patients both tests were pathological, while in 10/36 they were both normal; 14/36 patients had pathological OP reflux,
CONCLUSION: The correlation between OP pHmetry and pHMII was weak. At present, the absence of a reliable gold standard for the diagnosis of LPR and the uncertain etiology of the pharyngeal pH alterations make it difficult to decide which is the most reliable technique for the diagnosis of true LPR.