“Chronic Cough and Obstructive Sleep Apnoea: Reflux-associated Cough Hypersensitivity?”September 25, 2017
“Oropharyngeal pH Evaluation to Determine the Presence of Airway Reflux in Asthmatic Patients”September 25, 2017
Friedman M, Maley A, Kelley K, et al. Otolaryngol Head Neck Surg. 2011;144(4):558-62.
OBJECTIVES: Treatment of laryngopharyngeal reflux (LPR) often suffers from poor patient compliance and hence poor symptom improvement. The aim of this study was to determine whether 24-hour oropharyngeal pH monitoring was associated with higher rates of treatment compliance and symptom improvement compared with empirical treatment for LPR.
RESULTS: One-hundred and seventy patients were included in 2 groups. Group I consisted of 73 patients who underwent pH monitoring. Group II consisted of 70 patients treated empirically. Compliance with medication therapy (68.5% vs 50.0%, P = .019) and lifestyle modification (82.2 vs 25.7%, P = .0001) were greater among patients in group I. Symptom improvement was greater among patients in group I following treatment compared with patients in group II, with a significantly greater reduction in RSI (36.6% vs 24.4%, P = .023).
CONCLUSION: Among our patient population, treatment of LPR based on pH monitoring resulted in greater compliance, as well as greater symptom improvement, compared with empirical therapy alone.