“Limited Ability of the Proton-pump Inhibitor Test to Identify Patients with Gastroesophageal Reflux Disease”
September 20, 2017“Continuous Measurement of Intra-Oral pH and Temperature: Development Validation of an Appliance and a Pilot Study”
September 20, 2017Gorecka-Tuteja A, Jastrzebska I, Skladzien J, Fyderek K. J Neurogastroenterol Motil. 2016 Jul; 22(3): 452–458.
OBJECTIVES: To evaluate the characteristic properties of laryngopharyngeal reflux (LPR) and gastroesophageal reflux (GER) in children with otitis media with effusion (OME) using 24-hour multichannel intraluminal impedance combined with dual-probe (pharyngeal and esophageal) pH-metry.
RESULTS: Twenty-eight children were enrolled; LPR was detected in 19 (67.9%) children. The criteria of the LPR diagnosis was the presence of at least one supraesophageal episode with a pH < 5.0 and a change in the pH value measured from the initial level at the upper sensor of > 0.2. In total, 64 episodes were observed. Assessment of all LPR episodes showed the presence of 246 episodes in the entire study. A considerable predominance of weakly acidic episodes (87.8%) was noted; there were 6.5% acidic episodes, and weakly alkaline episodes reached 5.7%. Pathological GER was noted in 10 (35.7%) subjects. Acid GER was detected in 8 children, 2 of whom demonstrated non-acidic reflux. In the LPR-negative patients, no pathological GER was confirmed with the exception of a single case of non-acidic reflux.
CONCLUSION: LPR was frequently noted in the group of children with OME, and it might be an important risk factor in this common disease.